1cyd

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Template:STRUCTURE 1cyd

Contents

CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL

Template:ABSTRACT PUBMED 8805511

Function

[CBR2_MOUSE] May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism.[1]

About this Structure

1cyd is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Tanaka N, Nonaka T, Nakanishi M, Deyashiki Y, Hara A, Mitsui Y. Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure. 1996 Jan 15;4(1):33-45. PMID:8805511
  1. ↑ Nakanishi M, Deyashiki Y, Ohshima K, Hara A. Cloning, expression and tissue distribution of mouse tetrameric carbonyl reductase. Identity with an adipocyte 27-kDa protein. Eur J Biochem. 1995 Mar 1;228(2):381-7. PMID:7705352

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