1w8c

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Template:STRUCTURE 1w8c

Contents 1 CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL-9H-PURIN-2- YLAMINE AND MONOMERIC CDK2 2 About this Structure 3 See Also 4 Reference

CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL-9H-PURIN-2- YLAMINE AND MONOMERIC CDK2

Template:ABSTRACT PUBMED 24304238

About this Structure

1w8c is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2

Reference

• Carbain B, Paterson DJ, Anscombe E, Campbell-Dexter A, Cano C, Echalier A, Endicott J, Golding BT, Haggerty K, Hardcastle IR, Jewsbury PJ, Newell DR, Noble M, Roche C, Wang LZ, Griffin RJ. 8-Substituted O6-Cyclohexylmethylguanine CDK2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode. J Med Chem. 2013 Dec 4. PMID:24304238 doi:http://dx.doi.org/10.1021/jm401555v