1xa8

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Template:STRUCTURE 1xa8

Contents 1 Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa) 2 Function 3 About this Structure 4 Reference

Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa)

Template:ABSTRACT PUBMED 15548539

Function

[GFA_PARDE] Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.^[1]

About this Structure

1xa8 is a 4 chain structure with sequence from Paracoccus denitrificans. Full crystallographic information is available from OCA.

Reference

• Neculai AM, Neculai D, Griesinger C, Vorholt JA, Becker S. A dynamic zinc redox switch. J Biol Chem. 2005 Jan 28;280(4):2826-30. Epub 2004 Nov 17. PMID:15548539 doi:10.1074/jbc.C400517200

1. ↑ Goenrich M, Bartoschek S, Hagemeier CH, Griesinger C, Vorholt JA. A glutathione-dependent formaldehyde-activating enzyme (Gfa) from Paracoccus denitrificans detected and purified via two-dimensional proton exchange NMR spectroscopy. J Biol Chem. 2002 Feb 1;277(5):3069-72. Epub 2001 Dec 10. PMID:11741920 doi:10.1074/jbc.C100579200