1ryw

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Template:STRUCTURE 1ryw

Contents 1 C115S MurA liganded with reaction products 2 Function 3 About this Structure 4 See Also 5 Reference

C115S MurA liganded with reaction products

Template:ABSTRACT PUBMED 15531591

Function

[MURA_ENTCL] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.

About this Structure

1ryw is a 8 chain structure with sequence from Enterobacter cloacae. Full crystallographic information is available from OCA.

See Also

• Enoylpyruvate transferase

Reference

• Eschenburg S, Priestman M, Schonbrunn E. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem. 2005 Feb 4;280(5):3757-63. Epub 2004 Nov 5. PMID:15531591 doi:10.1074/jbc.M411325200