1jg3

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Template:STRUCTURE 1jg3

Contents

Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with adenosine & VYP(ISP)HA substrate

Template:ABSTRACT PUBMED 11700066

Function

[PIMT_PYRFU] Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity).

About this Structure

1jg3 is a 4 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA.

Reference

  • Griffith SC, Sawaya MR, Boutz DR, Thapar N, Katz JE, Clarke S, Yeates TO. Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate. J Mol Biol. 2001 Nov 9;313(5):1103-16. PMID:11700066 doi:10.1006/jmbi.2001.5095

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OCA

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