1p33

From Proteopedia

Revision as of 11:06, 16 April 2014 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 1p33

Contents

Pteridine reductase from Leishmania tarentolae complex with NADPH and MTX

Template:ABSTRACT PUBMED 12925782

Function

[PTR1_LEITA] Exhibits a NADPH-dependent biopterin reductase activity. Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin. Confers resistance to methotrexate (MTX).

About this Structure

1p33 is a 4 chain structure with sequence from Leishmania tarentolae. Full crystallographic information is available from OCA.

See Also

Reference

  • Zhao H, Bray T, Ouellette M, Zhao M, Ferre RA, Matthews D, Whiteley JM, Varughese KI. Structure of pteridine reductase (PTR1) from Leishmania tarentolae. Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1539-44. Epub 2003, Aug 19. PMID:12925782

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1p33"
Personal tools