1a1i

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Template:STRUCTURE 1a1i

Contents

RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCAC SITE)

Template:ABSTRACT PUBMED 9562555

Function

[EGR1_MOUSE] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

About this Structure

1a1i is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Elrod-Erickson M, Benson TE, Pabo CO. High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition. Structure. 1998 Apr 15;6(4):451-64. PMID:9562555

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OCA

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