1fi1
From Proteopedia
Contents |
FhuA in complex with lipopolysaccharide and rifamycin CGP4832
Template:ABSTRACT PUBMED 11587645
Function
[FHUA_ECOLI] This receptor binds the ferrichrome-iron ligand. It interacts with the TonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin.[1]
About this Structure
1fi1 is a 1 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.
Reference
- Ferguson AD, Kodding J, Walker G, Bos C, Coulton JW, Diederichs K, Braun V, Welte W. Active transport of an antibiotic rifamycin derivative by the outer-membrane protein FhuA. Structure. 2001 Aug;9(8):707-16. PMID:11587645
- ↑ Bonhivers M, Ghazi A, Boulanger P, Letellier L. FhuA, a transporter of the Escherichia coli outer membrane, is converted into a channel upon binding of bacteriophage T5. EMBO J. 1996 Apr 15;15(8):1850-6. PMID:8617231
Categories: Ecoli | Boes, C. | Braun, V. | Coulton, J W. | Diederichs, K. | Ferguson, A D. | Koedding, J. | Walker, G. | Welte, W. | Antibiotic | Beta-barrel | Fhua | Integral membrane protein | Lipopolysaccharide | Metal transport | Outer membrane protein | Rifamycin cgp 4832 | Siderophore receptor | Tonb-dependent receptor