1n5m

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Template:STRUCTURE 1n5m

Contents 1 Crystal structure of the mouse acetylcholinesterase-gallamine complex 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal structure of the mouse acetylcholinesterase-gallamine complex

Template:ABSTRACT PUBMED 12505979

Function

[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

About this Structure

1n5m is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

See Also

• Acetylcholinesterase

Reference

• Bourne Y, Taylor P, Radic Z, Marchot P. Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site. EMBO J. 2003 Jan 2;22(1):1-12. PMID:12505979 doi:http://dx.doi.org/10.1093/emboj/cdg005