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1e07

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Template:STRUCTURE 1e07

Contents

Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data

Template:ABSTRACT PUBMED 10854848

Function

[CEAM5_HUMAN] Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.[1]

About this Structure

1e07 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Boehm MK, Perkins SJ. Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. FEBS Lett. 2000 Jun 9;475(1):11-6. PMID:10854848
  1. Taheri M, Saragovi U, Fuks A, Makkerh J, Mort J, Stanners CP. Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion. J Biol Chem. 2000 Sep 1;275(35):26935-43. PMID:10864933 doi:10.1074/jbc.M909242199

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