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2cmh

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Template:STRUCTURE 2cmh

Contents

Crystal Structure of Spermidine Synthase from Helicobacter Pylori

Template:ABSTRACT PUBMED 17357156

Function

[SPEE_HELPY] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor.[1]

About this Structure

2cmh is a 3 chain structure with sequence from Campylobacter pylori. Full crystallographic information is available from OCA.

See Also

Reference

  • Lu PK, Tsai JY, Chien HY, Huang H, Chu CH, Sun YJ. Crystal structure of Helicobacter pylori spermidine synthase: a Rossmann-like fold with a distinct active site. Proteins. 2007 May 15;67(3):743-54. PMID:17357156 doi:10.1002/prot.21315
  1. Lee MJ, Huang CY, Sun YJ, Huang H. Cloning and characterization of spermidine synthase and its implication in polyamine biosynthesis in Helicobacter pylori strain 26695. Protein Expr Purif. 2005 Oct;43(2):140-8. PMID:16009566 doi:http://dx.doi.org/S1046-5928(05)00153-1

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