1ezr

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Template:STRUCTURE 1ezr

Contents

CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR

Template:ABSTRACT PUBMED 10409664

Function

[IUNH_LEIMA] Catalyzes the hydrolysis of all of the commonly occurring purine and pyrimidine nucleosides into ribose and the associated base, but has a preference for inosine and uridine as substrates.[1]

About this Structure

1ezr is a 4 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA.

Reference

  • Shi W, Schramm VL, Almo SC. Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. J Biol Chem. 1999 Jul 23;274(30):21114-20. PMID:10409664
  1. ↑ Shi W, Schramm VL, Almo SC. Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. J Biol Chem. 1999 Jul 23;274(30):21114-20. PMID:10409664

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