2ctx

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Template:STRUCTURE 2ctx

Contents

THE REFINED CRYSTAL STRUCTURE OF ALPHA-COBRATOXIN FROM NAJA NAJA SIAMENSIS AT 2.4-ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 1939183

Function

[NXL3_NAJNA] Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (only alpha-7 alpha-8 alpha-9) nicotinic acetylcholine receptors (By similarity).

About this Structure

2ctx is a 1 chain structure with sequence from Naja naja. Full crystallographic information is available from OCA.

Reference

  • Betzel C, Lange G, Pal GP, Wilson KS, Maelicke A, Saenger W. The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution. J Biol Chem. 1991 Nov 15;266(32):21530-6. PMID:1939183

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