2b2k

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Template:STRUCTURE 2b2k

Contents 1 structure of Y104F IDI-1 mutant in complex with EIPP 2 Function 3 About this Structure 4 Reference

structure of Y104F IDI-1 mutant in complex with EIPP

Template:ABSTRACT PUBMED 16617181

Function

[IDI_ECOLI] Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).^{[1] [2]}

About this Structure

2b2k is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

• de Ruyck J, Durisotti V, Oudjama Y, Wouters J. Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography. J Biol Chem. 2006 Jun 30;281(26):17864-9. Epub 2006 Apr 15. PMID:16617181 doi:http://dx.doi.org/10.1074/jbc.M601851200

1. ↑ Wang CW, Oh MK, Liao JC. Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli. Biotechnol Bioeng. 1999 Jan 20;62(2):235-41. PMID:10099534
2. ↑ Hemmi H, Ohnuma S, Nagaoka K, Nishino T. Identification of genes affecting lycopene formation in Escherichia coli transformed with carotenoid biosynthetic genes: candidates for early genes in isoprenoid biosynthesis. J Biochem. 1998 Jun;123(6):1088-96. PMID:9603997