1vsg

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Template:STRUCTURE 1vsg

Contents 1 2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI 2 Function 3 About this Structure 4 Reference

2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI

Template:ABSTRACT PUBMED 2231728

Function

[VSM2_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.

About this Structure

1vsg is a 2 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

• Freymann D, Down J, Carrington M, Roditi I, Turner M, Wiley D. 2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei. J Mol Biol. 1990 Nov 5;216(1):141-60. PMID:2231728