1hyu

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Template:STRUCTURE 1hyu

Contents

CRYSTAL STRUCTURE OF INTACT AHPF

Template:ABSTRACT PUBMED 11300769

Function

[AHPF_SALTY] Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

About this Structure

1hyu is a 1 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.

Reference

  • Wood ZA, Poole LB, Karplus PA. Structure of intact AhpF reveals a mirrored thioredoxin-like active site and implies large domain rotations during catalysis. Biochemistry. 2001 Apr 3;40(13):3900-11. PMID:11300769

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