289d

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Image:289d.png

Template:STRUCTURE 289d

TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2

Template:ABSTRACT PUBMED 8917643

About this Structure

289d is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Trent JO, Clark GR, Kumar A, Wilson WD, Boykin DW, Hall JE, Tidwell RR, Blagburn BL, Neidle S. Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2. J Med Chem. 1996 Nov 8;39(23):4554-62. PMID:8917643 doi:10.1021/jm9604484
  • Nguyen B, Neidle S, Wilson WD. A role for water molecules in DNA-ligand minor groove recognition. Acc Chem Res. 2009 Jan 20;42(1):11-21. PMID:18798655 doi:10.1021/ar800016q

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