1jhn

From Proteopedia

Revision as of 11:22, 21 February 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1jhn.gif

1jhn, resolution 2.9Å

Drag the structure with the mouse to rotate

Crystal Structure of the Lumenal Domain of Calnexin

Overview

The three-dimensional structure of the lumenal domain of the lectin-like chaperone calnexin determined to 2.9 A resolution reveals an extended 140 A arm inserted into a beta sandwich structure characteristic of legume lectins. The arm is composed of tandem repeats of two proline-rich sequence motifs which interact with one another in a head-to-tail fashion. Identification of the ligand binding site establishes calnexin as a monovalent lectin, providing insight into the mechanism by which the calnexin family of chaperones interacts with monoglucosylated glycoproteins.

About this Structure

1JHN is a Single protein structure of sequence from Canis lupus familiaris with as ligand. Full crystallographic information is available from OCA.

Reference

The Structure of calnexin, an ER chaperone involved in quality control of protein folding., Schrag JD, Bergeron JJ, Li Y, Borisova S, Hahn M, Thomas DY, Cygler M, Mol Cell. 2001 Sep;8(3):633-44. PMID:11583625

Page seeded by OCA on Thu Feb 21 13:22:43 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jhn"
Personal tools