3zhg

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Template:STRUCTURE 3zhg

Crystallographic structure of the native mouse SIGN-R1 CRD domain

Function

[C209B_MOUSE] Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

About this Structure

3zhg is a 4 chain structure. Full crystallographic information is available from OCA.

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