3coh
From Proteopedia
Crystal structure of Aurora-A in complex with a pentacyclic inhibitor
Template:ABSTRACT PUBMED 18630890
About this Structure
3coh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rawson TE, Ruth M, Blackwood E, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Georges GJ, Goller B, Halladay J, Hunsaker T, Kleinheinz T, Krell HW, Li J, Liang J, Limberg A, McNutt A, Moffat J, Phillips G, Ran Y, Safina B, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhou A, Zhu BY, Ruger P, Cochran AG. A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. J Med Chem. 2008 Aug 14;51(15):4465-75. Epub 2008 Jul 17. PMID:18630890 doi:10.1021/jm800052b
