3ubh

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Template:STRUCTURE 3ubh

Contents

Crystal structure of Drosophila N-cadherin EC1-4

Template:ABSTRACT PUBMED 22171007

Function

[CADN_DROME] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May associate with arm neural isoform and participate in the transmission of developmental information.

About this Structure

3ubh is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Jin X, Walker MA, Felsovalyi K, Vendome J, Bahna F, Mannepalli S, Cosmanescu F, Ahlsen G, Honig B, Shapiro L. Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers. Proc Natl Acad Sci U S A. 2011 Dec 14. PMID:22171007 doi:10.1073/pnas.1117538108

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