3utz

From Proteopedia

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Template:STRUCTURE 3utz

Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential

Template:ABSTRACT PUBMED 22198278

About this Structure

3utz is a 6 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

• Sela-Passwell N, Kikkeri R, Dym O, Rozenberg H, Margalit R, Arad-Yellin R, Eisenstein M, Brenner O, Shoham T, Danon T, Shanzer A, Sagi I. Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. Nat Med. 2011 Dec 25;18(1):143-7. doi: 10.1038/nm.2582. PMID:22198278 doi:10.1038/nm.2582