Insulin-like growth factor

Insulin-like growth factor (IGF) are proteins with high sequence similarity to insulin. IGF are ligands in a complex called the IGF axis, which contains 2 IGF receptors, 6 IGF-binding proteins and IGF-binding protein degrading enzyme.

• IGF I is secreted in the liver after stimulation by growth hormone.
  
• IGF II is required in early development stages.

3D structures of insulin-like growth factor

Updated on 27-November-2014