3fuc

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Template:STRUCTURE 3fuc

Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'-phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit

Template:ABSTRACT PUBMED 19944078

About this Structure

3fuc is a 3 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Chojnowski G, Breer K, Narczyk M, Wielgus-Kutrowska B, Czapinska H, Hashimoto M, Hikishima S, Yokomatsu T, Bochtler M, Girstun A, Staron K, Bzowska A. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state. Biochem Biophys Res Commun. 2010 Jan 1;391(1):703-8. Epub 2009 Nov 26. PMID:19944078 doi:10.1016/j.bbrc.2009.11.124

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