Retinoblastoma-binding protein

From Proteopedia

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Template:STRUCTURE 3cfs

Retinoblastoma-binding protein (RBBP) are nuclear proteins implicated in the regulation of transcription and differentiation by the retinoblastoma tumor suppressor protein.

• RBBP1 regulates transcriptional activity.
  
• RBBP2 demethylates histone H3 at lysine 4.
  
• RBBP5 is involved in methylation and dimethylation of histone H3.
  
• RBBP9 blocks the binding of retinoblastoma protein to one of its signaling partners.

Contents 1 3D structures of retinoblastoma-binding protein 1.1 RBBP1 1.2 RBBP2 1.3 RBBP4 1.4 RBBP6 1.5 RBBP7 1.6 RBBP9

3D structures of retinoblastoma-binding protein

RBBP1

2yrv, 2lcc – hRBBP1 AT-rich interactive domain – human – NMR

RBBP2

2jxj – hRBBP2 ARID domain + histone H3 – NMR
2kgg – hRBBP2 C terminal PHD zinc finger – NMR
2kgi - hRBBP2 C terminal PHD zinc finger + histone H3 – NMR
3gl6 - hRBBP2 C terminal PHD zinc finger + histone H3 N terminal

RBBP4

3gfc – hRBBP4
2xu7 – hRBBP4 + zinc finger protein ZFPM1 RBBP4-binding domain

RBBP6

2c7h – hRBBP6 DWNN domain – NMR
2ysa - hRBBP6 zinc finger CCHC domain – NMR
2yur, 3ztg - hRBBP6 ring finger domain – NMR

RBBP7

3cfs, 3cfv – hRBBP7 + histone H4 helix

RBBP9

2qs9 – hRBBP9