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3hvr

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Image:3hvr.png

Template:STRUCTURE 3hvr

Crystal structure of T. thermophilus Argonaute complexed with DNA guide strand and 19-nt RNA target strand with two Mg2+ at the cleavage site

Template:ABSTRACT PUBMED 19812667

About this Structure

3hvr is a 6 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

  • Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature. 2009 Oct 8;461(7265):754-61. PMID:19812667 doi:10.1038/nature08434

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