Ribosomal protein L11 methyltransferase

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Template:STRUCTURE 2nxc

Ribosomal protein L11 methyltransferase (L11 MTase) catalyzes the methylation of ribosomal protein L11 (RPL11). L11 MTase methylates the N terminal of RPL11 and residues Lys3 and Lys39.

3D Structures of Ribosomal protein L11 methyltransferase

L11 MTase

3grz – L11 MTase C-terminal – Lactobacillus delbruekii
2nxc, 2nxj - TtL11 MTase - Thermus thermophilus
2zbp, 2zbq, 2zbr, 2nxe– TtL11 MTase+S-adenosyl derivatives

L11 Mtase+RPL11

3egv, 2nxn – TtL11 Mtase+RPL11
3cjq - TtL11 Mtase+RPL11 (mutant)
3cjr - TtL11 Mtase+RPL11 (mutant)+sinefungin
3cjs - TtL11 Mtase N-terminal+RPL11 N-terminal
3cjt - TtL11 Mtase (mutant)+RPL11

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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