3qjz

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Image:3qjz.png

Template:STRUCTURE 3qjz

Contents

Crystal structure of PI3K-gamma in complex with benzothiazole 1

Template:ABSTRACT PUBMED 21332118

About this Structure

3qjz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • D'Angelo ND, Kim TS, Andrews K, Booker SK, Caenepeel S, Chen K, D'Amico D, Freeman D, Jiang J, Liu L, McCarter JD, San Miguel T, Mullady EL, Schrag M, Subramanian R, Tang J, Wahl RC, Wang L, Whittington DA, Wu T, Xi N, Xu Y, Yakowec P, Yang K, Zalameda LP, Zhang N, Hughes P, Norman MH. Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors. J Med Chem. 2011 Mar 24;54(6):1789-811. Epub 2011 Feb 18. PMID:21332118 doi:10.1021/jm1014605

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