3pj8

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Template:STRUCTURE 3pj8

Contents 1 Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine. 2 About this Structure 3 See Also 4 Reference

Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine.

Template:ABSTRACT PUBMED 21417417

About this Structure

3pj8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2

Reference

• Jorda R, Havlicek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navratilova J, Kuzma M, Mistrik M, Bartek J, Strnad M, Krystof V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-dependent Kinases with Antiproliferative Activity. J Med Chem. 2011 Mar 21. PMID:21417417 doi:10.1021/jm200064p