3uhm

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Template:STRUCTURE 3uhm

UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor

Template:ABSTRACT PUBMED 22257165

About this Structure

3uhm is a 1 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Montgomery JI, Brown MF, Reilly U, Price LM, Abramite JA, Arcari J, Barham RA, Che Y, Chen JM, Chung SW, Collantes EM, Desbonnet C, Doroski M, Doty J, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, McAllister LA, McElroy E, Menard C, Mitton-Fry M, Mullins L, Noe MC, O'Donnell JP, Oliver R, Penzien J, Plummer M, Shanmugasundaram V, Thoma C, Tomaras AP, Uccello DP, Vaz AD, Wishka DG. Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections. J Med Chem. 2012 Jan 18. PMID:22257165 doi:10.1021/jm2014875

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