3vf3

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Image:3vf3.jpg

Template:STRUCTURE 3vf3

Crystal Structure of Human Beta Secretase in Complex with NVP-BQQ711

Template:ABSTRACT PUBMED 22380629

About this Structure

3vf3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rueeger H, Rondeau JM, McCarthy C, Mobitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. Epub 2011 Feb 15. PMID:21388807 doi:10.1016/j.bmcl.2011.02.038

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OCA

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