2lc3

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Template:STRUCTURE 2lc3

Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A

Function

[HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).

About this Structure

2lc3 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

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