2wq9
From Proteopedia
Contents |
CRYSTAL STRUCTURE OF RBP4 BOUND TO OLEIC ACID
Disease
[RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Function
[RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
About this Structure
2wq9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
