2yog

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Template:STRUCTURE 2yog

Plasmodium falciparum thymidylate kinase in complex with a (thio)urea- alpha-deoxythymidine inhibitor

Template:ABSTRACT PUBMED 23240776

About this Structure

2yog is a 2 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

Cui H, Carrero-Lerida J, Silva AP, Whittingham JL, Brannigan JA, Ruiz-Perez LM, Read KD, Wilson KS, Gonzalez-Pacanowska D, Gilbert IH. Synthesis and evaluation of alpha-thymidine analogues as novel antimalarials. J Med Chem. 2012 Dec 27;55(24):10948-57. doi: 10.1021/jm301328h. Epub 2012 Dec, 14. PMID:23240776 doi:10.1021/jm301328h

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Retrieved from "http://52.214.119.220/wiki/index.php/2yog"

Categories: Plasmodium falciparum 3d7 | DTMP kinase | Brannigan, J A. | Carrero-Lerida, J. | Gilbert, I H. | Gonzalez-Pacanowska, D. | Huaqing, C. | Read, K D. | Ruiz-Perez, L M. | Silva, A P.G. | Whittingham, J L. | Wilson, K S. | Inhibitor | Malaria | Transferase

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