3aqx

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Template:STRUCTURE 3aqx

Contents 1 Crystal structure of Bombyx mori beta-GRP/GNBP3 N-terminal domain with laminarihexaoses 2 Function 3 About this Structure 4 Reference

Crystal structure of Bombyx mori beta-GRP/GNBP3 N-terminal domain with laminarihexaoses

Template:ABSTRACT PUBMED 21697086

Function

[BGBP_BOMMO] Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade.^{[1] [2]}

About this Structure

3aqx is a 2 chain structure with sequence from Bombyx mori. Full crystallographic information is available from OCA.

Reference

• Kanagawa M, Satoh T, Ikeda A, Adachi Y, Ohno N, Yamaguchi Y. Structural insights into recognition of triple-helical {beta}-glucan by insect fungal receptor. J Biol Chem. 2011 Jun 22. PMID:21697086 doi:10.1074/jbc.M111.256701

1. ↑ Ochiai M, Ashida M. A pattern-recognition protein for beta-1,3-glucan. The binding domain and the cDNA cloning of beta-1,3-glucan recognition protein from the silkworm, Bombyx mori. J Biol Chem. 2000 Feb 18;275(7):4995-5002. PMID:10671539
2. ↑ Ochiai M, Ashida M. Purification of a beta-1,3-glucan recognition protein in the prophenoloxidase activating system from hemolymph of the silkworm, Bombyx mori. J Biol Chem. 1988 Aug 25;263(24):12056-62. PMID:3136171