3n7e

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Template:STRUCTURE 3n7e

Contents 1 Crystal structure of CopK bound to Cu(II) 2 Function 3 About this Structure 4 Reference

Crystal structure of CopK bound to Cu(II)

Template:ABSTRACT PUBMED 021936507

Function

[COPK_RALME] Involved in resistance to copper. Can bind up to 2 copper ions. Has higher affinity for Cu(+) than for Cu(2+).^[1]

About this Structure

3n7e is a 2 chain structure with sequence from Cupriavidus metallidurans. Full crystallographic information is available from OCA.

Reference

• Ash MR, Chong LX, Maher MJ, Hinds MG, Xiao Z, Wedd AG. Molecular basis of the cooperative binding of Cu(I) and Cu(II) to the CopK protein from Cupriavidus metallidurans CH34. Biochemistry. 2011 Nov 1;50(43):9237-47. Epub 2011 Oct 4. PMID:21936507 doi:10.1021/bi200841f

1. ↑ Bersch B, Favier A, Schanda P, van Aelst S, Vallaeys T, Coves J, Mergeay M, Wattiez R. Molecular structure and metal-binding properties of the periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during copper challenge. J Mol Biol. 2008 Jul 4;380(2):386-403. Epub 2008 May 15. PMID:18533181 doi:10.1016/j.jmb.2008.05.017