3iwv

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Template:STRUCTURE 3iwv

Contents 1 Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) 2 Function 3 About this Structure 4 Reference

Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)

Template:ABSTRACT PUBMED 16952372

Function

[HIUH_DANRE] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

About this Structure

3iwv is a 4 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

• Zanotti G, Cendron L, Ramazzina I, Folli C, Percudani R, Berni R. Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter. J Mol Biol. 2006 Oct 13;363(1):1-9. Epub 2006 Aug 2. PMID:16952372 doi:10.1016/j.jmb.2006.07.079