3kz3

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Template:STRUCTURE 3kz3

Contents

A structure of a lambda repressor fragment mutant

Template:ABSTRACT PUBMED 20138892

Function

[RPC1_LAMBD] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.

About this Structure

3kz3 is a 2 chain structure with sequence from Enterobacteria phage lambda. Full crystallographic information is available from OCA.

Reference

  • Liu F, Gao YG, Gruebele M. A survey of lambda repressor fragments from two-state to downhill folding. J Mol Biol. 2010 Apr 2;397(3):789-98. Epub 2010 Feb 6. PMID:20138892 doi:10.1016/j.jmb.2010.01.071

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