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3mvf

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Template:STRUCTURE 3mvf

Contents

Crystal Structure of Nitrophorin 4 from Rhodnius prolixus Complexed with Nitrite at pH 7.4

Template:ABSTRACT PUBMED 20524697

Function

[NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).

About this Structure

3mvf is a 1 chain structure with sequence from Rhodnius prolixus. Full crystallographic information is available from OCA.

Reference

  • He C, Ogata H, Knipp M. Complex Formation of Nitrite with the Ferriheme b beta-Barrel Proteins Nitrophorin 4 and Nitrophorin 7. Biochemistry. 2010 Jun 4. PMID:20524697 doi:10.1021/bi100324z

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