3kyg

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Template:STRUCTURE 3kyg

Contents

Crystal structure of VCA0042 (L135R) complexed with c-di-GMP

Template:ABSTRACT PUBMED 20226196

Function

[Q9KNC3_VIBCH] May act as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (Potential). Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) with a dissociation constant of 170 nM in the presence of 10 mM KCl and with 100 mM in its absence.[HAMAP-Rule:MF_01457]

About this Structure

3kyg is a 2 chain structure with sequence from Vibrio cholerae. Full crystallographic information is available from OCA.

Reference

  • Ko J, Ryu KS, Kim H, Shin JS, Lee JO, Cheong C, Choi BS. Structure of PP4397 reveals the molecular basis for different c-di-GMP binding modes by Pilz domain proteins. J Mol Biol. 2010 Apr 23;398(1):97-110. Epub 2010 Mar 10. PMID:20226196 doi:10.1016/j.jmb.2010.03.007

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