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3ngx

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Template:STRUCTURE 3ngx

Contents

Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum

Template:ABSTRACT PUBMED 21333632

Function

[FOLD_THEAC] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).

About this Structure

3ngx is a 2 chain structure with sequence from Thermoplasma acidophilum. Full crystallographic information is available from OCA.

Reference

  • Lee WH, Sung MW, Kim JH, Kim YK, Han A, Hwang KY. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011 Mar 18;406(3):459-63. Epub 2011 Feb 17. PMID:21333632 doi:10.1016/j.bbrc.2011.02.074

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OCA

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