3nf3

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Template:STRUCTURE 3nf3

Crystal structure of BoNT/A LC with JTH-NB-7239 peptide

Template:ABSTRACT PUBMED 20614028

About this Structure

3nf3 is a 2 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.

Reference

Zuniga JE, Hammill JT, Drory O, Nuss JE, Burnett JC, Gussio R, Wipf P, Bavari S, Brunger AT. Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. PLoS One. 2010 Jun 30;5(6):e11378. PMID:20614028 doi:10.1371/journal.pone.0011378

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Categories: Clostridium botulinum | Zuniga, J E. | Botulinum neurotoxin | Botulism | Hydrolase | Hydrolase-hydrolase inhibitor complex | Inhibition | Membrane | Metal-binding | Metalloprotease | Neuromuscular junction | Neurotransmission | Protease | Secreted | Snare | Toxin

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