3n59
From Proteopedia
Contents |
Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate
Template:ABSTRACT PUBMED 21410435
Function
[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
About this Structure
3n59 is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
Categories: 3-dehydroquinate dehydratase | Mycobacterium tuberculosis | Abell, C. | Blundell, T L. | Bromfield, K M. | Ciulli, A. | Dias, M V.B. | Howard, N I. | Palaninathan, S K. | Payne, R. | Sacchettini, J C. | Snee, W C. | TBSGC, TB Structural Genomics Consortium. | 3-dehydroshikimate | Aromatic amino acid biosynthesis | Dehydratase | Drug target | Lyase | Shikimate pathway | Structural genomic | Tb structural genomics consortium | Tbsgc | Tuberculosis
