3lrb

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Template:STRUCTURE 3lrb

Contents

Structure of E. coli AdiC

Template:ABSTRACT PUBMED 19478139

Function

[ADIC_ECO57] Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons.

About this Structure

3lrb is a 2 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 3h5m. Full crystallographic information is available from OCA.

Reference

  • Gao X, Lu F, Zhou L, Dang S, Sun L, Li X, Wang J, Shi Y. Structure and mechanism of an amino acid antiporter. Science. 2009 Jun 19;324(5934):1565-8. Epub 2009 May 28. PMID:19478139

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