3izy

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Template:STRUCTURE 3izy

Contents

Mammalian mitochondrial translation initiation factor 2

Template:ABSTRACT PUBMED 21368145

Function

[IF2M_BOVIN] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

About this Structure

3izy is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Yassin AS, Haque ME, Datta PP, Elmore K, Banavali NK, Spremulli LL, Agrawal RK. Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3918-23. Epub 2011 Feb 22. PMID:21368145 doi:10.1073/pnas.1017425108

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OCA

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