3n87
From Proteopedia
Contents |
Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3
Template:ABSTRACT PUBMED 21410435
Function
[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
About this Structure
3n87 is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
Categories: 3-dehydroquinate dehydratase | Mycobacterium tuberculosis | Abell, C. | Blundell, T L. | Bromfield, K M. | Ciulli, A. | Dias, M V.B. | Howard, N I. | Palaninathan, S K. | Payne, R. | Sacchettini, J C. | Snee, W C. | Arod | Dehydroquinate dehydratase | Drug discovery | Lyase | Lyase-lyase inhibitor complex | Shikimate pathway
