3jwn

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Template:STRUCTURE 3jwn

Contents

Complex of FimC, FimF, FimG and FimH

Template:ABSTRACT PUBMED 20478255

Function

[FIMC_ECOLI] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [FIMG_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae. [FIMF_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Involved in the integration of FimH in the fimbriae.

About this Structure

3jwn is a 10 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Le Trong I, Aprikian P, Kidd BA, Forero-Shelton M, Tchesnokova V, Rajagopal P, Rodriguez V, Interlandi G, Klevit R, Vogel V, Stenkamp RE, Sokurenko EV, Thomas WE. Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like beta sheet twisting. Cell. 2010 May 14;141(4):645-55. PMID:20478255 doi:10.1016/j.cell.2010.03.038

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