3p3c

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Template:STRUCTURE 3p3c

Contents

Crystal Structure of the Aquifex aeolicus LpxC/LPC-009 complex

Template:ABSTRACT PUBMED 21167751

Function

[LPXC_AQUAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).

About this Structure

3p3c is a 1 chain structure with sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.

Reference

  • Lee CJ, Liang X, Chen X, Zeng D, Joo SH, Chung HS, Barb AW, Swanson SM, Nicholas RA, Li Y, Toone EJ, Raetz CR, Zhou P. Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design. Chem Biol. 2010 Dec 16. PMID:21167751 doi:10.1016/j.chembiol.2010.11.011

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OCA

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