3pnb

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Template:STRUCTURE 3pnb

Contents

Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A

Template:ABSTRACT PUBMED 21543857

Function

[COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

About this Structure

3pnb is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Wubben T, Mesecar AD. Structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt, 5):541-5. Epub 2011 Apr 20. PMID:21543857 doi:10.1107/S1744309111010761

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