3ucs

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Template:STRUCTURE 3ucs

Contents 1 Crystal structure of the complex between CBPA J-domain and CBPM 2 Function 3 About this Structure 4 Reference

Crystal structure of the complex between CBPA J-domain and CBPM

Function

[CBPA_ECOLI] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.^{[1] [2]}

About this Structure

3ucs is a 4 chain structure with sequence from Escherichia coli k-12 and Klebsiella pneumoniae 342. Full crystallographic information is available from OCA.

Reference

1. ↑ Ueguchi C, Shiozawa T, Kakeda M, Yamada H, Mizuno T. A study of the double mutation of dnaJ and cbpA, whose gene products function as molecular chaperones in Escherichia coli. J Bacteriol. 1995 Jul;177(13):3894-6. PMID:7601860
2. ↑ Wegrzyn A, Taylor K, Wegrzyn G. The cbpA chaperone gene function compensates for dnaJ in lambda plasmid replication during amino acid starvation of Escherichia coli. J Bacteriol. 1996 Oct;178(19):5847-9. PMID:8824642